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Mouse models are widely used to study heat-related physiological responses as they provide insights relevant to human health. However, species differences (including nocturnal behavior) and standard housing below the thermoneutral zone (TNZ; 26°C-34°C) can confound comparisons. This systematic review evaluates methodologies, including housing temperatures, used in mouse heat-exposure studies published over the past 4 years.
Deliberate exposure to ionizing radiation during medical investigations, such as chest CT, should be as low as reasonably practicable to reduce the risk of inducing cancer. Certain populations are at particular risk, such as those undergoing lung cancer screening and workers exposed to dust, and require multiple scans over time with high baseline risk.
Early childhood education and care (ECEC) is widely recognized for supporting children's development and school readiness; however, evidence from Western Australia remains limited.
This study examines whether nonstandard work schedules (NSWS) improve or hinder work-life balance (WLB) for parents and non-parents in dual-earner households.
People with intellectual disability experience significant gaps in healthcare delivery resulting in poor health outcomes. Appropriately designed healthcare is required to meet the needs of this population and achieve better health outcomes. Little is known about the structure of healthcare delivery for people with intellectual disability and whether it is effective or cost-effective.
To evaluate whether the General Movement Assessment in infancy is associated with later cognitive outcomes from early childhood through adulthood.
To explore the lived experiences of parents of children at risk of type 1 diabetes undergoing repeated blinded continuous glucose monitoring. Since 2021, children with persistent islet autoimmunity in the Environmental Determinants of Islet Autoimmunity study have been invited to participate in a sub-study involving blinded Dexcom G6 CGM.
Acute lymphoblastic leukaemia (ALL) is one of the most treatable forms of paediatric cancer; however, there is a substantial burden of treatment-related toxicities (TRTs). In addition, the long-term changes in children's health-related quality of life (HRQoL) due to toxic treatments are not well understood.
People with intellectual disability face significant barriers to accessing genetic healthcare, including during appointments. Many adults with intellectual disability are denied opportunities to discuss genetic testing that could improve their health and well-being.
More than 3,000 skin checks have been undertaken as part of a large clinical trial in WA’s Kimberley region aimed at halving the burden of skin sores in school-aged Aboriginal children.