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Regulating the Irregular: Phage Therapy and the Case for a Regulatory Sandbox Approach in Australia

Bacteriophages (phages) are viruses that selectively kill bacteria and offer a promising option to address the growing global pandemic of antimicrobial-resistant infections. However, phage therapy does not easily align with traditional regulatory pathways designed for fixed-composition chemical drugs or biologics with fixed non-evolving compositions.

The presentation of dissociative symptoms in childhood and early adolescence: A systematic review and thematic synthesis of 30 case studies

Dissociative disorders in children and young adolescents are under-recognised and under-treated. Current diagnostic criteria rely on downward extensions of adult models and do not adequately consider developmental differences in younger populations. This reliance risks overlooking symptom patterns that may be unique in childhood, thereby perpetuating diagnostic gaps and delayed treatment. 

"The absolute dearth of resources": Challenges and unmet support needs for emerging adult siblings of individuals with neurodevelopmental conditions in regional and remote Australia

Siblings of individuals with neurodevelopmental conditions have unique experiences and sometimes additional challenges, especially in rural areas where there may be limited access to sibling-specific support services. 

Reduced Prevalence of Impaired Awareness of Hypoglycemia Over Two Decades in Population-Based Samples of Youth With Type 1 Diabetes

To investigate the change in prevalence of impaired awareness of hypoglycemia (IAH) and severe hypoglycemia (SH) across three cohorts (2002, 2015, and 2024) in youth with type 1 diabetes.

Masculine Norm Adherence Among Australian Men: Latent Structure of the CMNI-22 and Its Links With Mental Health Outcomes

Masculine norms influence men's health and wellbeing. In Australia, interest in the role of these masculine norms resulted in an assessment of masculine norm adherence being included in the Ten to Men Study, measured using the 22-item version of the Conformity to Masculine Norms Inventory.

Long term lung health in children: new emerging threats and preventive strategies

The long-term consequences of early adverse exposures are well known but is becoming clear that early means not just in pregnancy but also in at least the two preceding generations. Furthermore, there are new existential threats to long term respiratory health, some of which have been presented at the INSPiRED meeting in Bologna and are reviewed in this manuscript.

The Time to Act Is Now: Strengthening Health Systems Research Capacity, Capability and Knowledge Translation in Remote Australia

Citation: Edelman A, Moore S, DeMasi K, Stephens DM, et al. The Time to Act Is Now: Strengthening Health Systems Research Capacity, Capability and

Trends and indications for cesarean section in the ORIGINS birth cohort

Cesarean section (CS) rates have increased substantially in Australia, with particularly high use observed in private maternity care and for pre-labor CS. The aim of the present study was to describe the CS rates and the clinical indications for pre-labor CS in the ORIGINS birth cohort.

Toxicity of plastic diesel exhaust in primary human airway epithelial cell cultures

Plastic pyrolysis oil, which can be produced with similar properties as diesel fuel (plastic diesel), can be used as an alternative to mineral diesel (ULSD) to run a diesel engine. This presents a potential method for recycling waste plastic. Typically plastic diesel is blended with mineral diesel, and oxygenated fuel additives such as ethers added to improve resulting fuel properties. 

Co-Producing the Australian Functional Strengths and Support Needs Framework: Approach, Experience and Outcomes

The study aimed to evaluate the experiences of participants involved in co-production to develop a National Framework for assessing children's functional strengths and support needs. The National Framework was developed to guide professionals when working with children aged 0-12 years, including children who do and do not have one or more diagnosed condition(s), and their families in Australia and inform good policy across health, education, disability, and community support sectors.