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Immune checkpoint blockade (ICB) evokes antitumor immunity through the reinvigoration of T cell responses. T cell differentiation status controls response, with less differentiated cells having an enhanced capacity to proliferate after ICB. Given that conventional type 1 dendritic cells (cDC1) maintain precursor exhausted T cells (TPEX), we hypothesized that expansion of cDC1s with Flt3L could enhance responses to ICB. 

The Education Department of Western Australia advocates for culturally responsive schools. Aboriginal Indigenous Education Officers are employed by schools to facilitate and enable the potential for Aboriginal school children to thrive in school settings. 

Citation: Wang KCW, Lawrence K, Wisnivesky JP, Diaz AA. Enhancing a diverse population: the American Thoracic Society Mentoring Program for

Heated-tobacco-products (HTPs) are electronic devices that "heat" a processed tobacco/chemical mixture to produce an inhalable emission. They are advertised as a reduced-risk alternative to cigarette smoking. The aim of our research was to assess their potential health impacts using a 3D human airway model.

There is a greater prevalence of multiple sclerosis (MS), a neurological autoimmune condition, in populations living further from the equator, hypothesised to be due to reduced sunlight exposure. There exists a proven sunlight surrogate therapy for dermatological inflammatory conditions, in the form of narrowband NB-UVB phototherapy. Yet, there is a paucity of randomized trials of the therapeutic delivery of NB-UVB beyond dermatology for conditions with a systemic inflammatory component. 

Men’s Sheds offer promising sites for unique health promotion opportunities, and while prior work has identified potential mechanisms that may support wellbeing, these mechanisms are yet to be empirically clarified in the Men’s Shed context. This study investigated the relationships between engagement in Men’s Sheds, social identification, social connectedness, social support, and wellbeing outcomes in Men’s Shed members in Western Australia.

We conducted the non-invasive surveillance of Plasmodium knowlesi in wild macaques using 4,752 faecal samples collected across nine endemic countries. 

With young adults' rates of mental health problems alarmingly high, understanding resilience characteristics that help young people adapt, adjust, and even thrive in the face of stress is a pressing need. This study takes a daily diary approach, examining four resilience factors, measured a priori, covering multiple domains. Young adults' daily stress responses (reactivity, recovery, inertia) during the globally stressful lockdown period three years later were then explored as key outcomes.

Indigenous communities are under-represented in genomics research, contributing to inequitable health-related knowledge, outcomes, and benefits. Under-representation reflects enduring consequences of colonial research practices that have engendered cultural, ethical, legal, and social (CELS) concerns among communities. 

Sensory integration therapy is used widely despite an inconsistent evidence base. To overcome the limited availability of high-quality research, Ayres Sensory Integration (ASI) was manualized and a revised fidelity measure was developed following the identification of the principles of ASI®. The aim of this systematic review is to examine the proximal and distal effects of interventions in studies that explicitly reported the use of or adherence to the process elements of the fidelity measure.