Determinants of culture success through retrospective analysis of a program of routinely brushing children with Cystic Fibrosis airway disease
We hypothesized that allergic inflammation decreases the level of circulating 25(OH)D and tested this using a mice model of house dust mite (HDM) ind…
Our results show that canola biodiesel exhaust exposure elicits inflammation and reduces viability of human epithelial cell cultures in vitro when co…
In this study, we compared the physiological consequences of short-term exposure to diesel exhaust via inhalation to those due to exposure to the sam…
In this study, we combined human-rhinovirus infection with a clinically relevant mouse model of aero-allergen exposure using house-dust-mite in an at…
The airway epithelium in asthma displays altered repair and incomplete barrier formation.
Dysregulated repair following epithelial injury is a key forerunner of disease in many organs, and the acquisition of a mesenchymal phenotype by the…
Allergic inflammation is commonly observed in a number of conditions that are associated with atopy including asthma, eczema and rhinitis.
The anti-inflammatory peptide, adrenomedullin (AM), and its cognate receptor are expressed in lung tissue, but its pathophysiological significance in…
Long-term survival after lung transplantation is hindered by the development of bronchiolitis obliterans syndrome (BOS).