Our current Research Topic highlights the complexity of the relationship between the skin, immune system and skin cancer
The review will outline evidence of long-term health effects, possible mechanisms linking burn injury to long-term health and current research into b…
Our results identify a pretreatment tumor microenvironment that predicts response to immune checkpoint blockade, which can be therapeutically attained
This review explores computational strategies to yield biological insight into the processes involved in the immunotherapeutic response
These findings suggest that tumor cells employ multiple epigenetic and genetic mechanisms to evade immune control
Our findings provide insight into the immune cell populations important for maintaining long-term tumour dormancy in peripheral tissues
We discovered a previously unknown major resistance mechanism in glioma in that most EGFR domain III-targeting antibodies do not neutralize EGFRvIII
In this review, we discuss the different subsets of tumor-infiltrating dendritic cells and their role in anti-tumor immunity
We present a curated panel of 12 readily-usable, cell lines representing the spectrum of molecular subtypes of IDH-wildtype glioblastoma
Our data demonstrate that CD8+XCR1neg DCs possess a unique pattern of endocytic receptors and a restricted TLR profile that is particularly enriched…