Published research
LYL1 is critical for adult hematopoietic stem cell-derived B and T lymphopoiesis
Hematopoietic stem cells are defined by their remarkable self-renewal and differentiation capacities, giving rise to progenitors that generate diverse blood and immune cell lineages through the tightly regulated process of hematopoiesis. This process is governed by key transcription factors that control gene expression programs essential for cellular homeostasis, differentiation, and lineage commitment.
Blinatumomab limits humoral antibody response despite boosting the influenza vaccine schedule in children with B-ALL
Preclinical Assessment of Dactinomycin in KMT2A-Rearranged Infant Acute Lymphoblastic Leukemia
Infants with KMT2A-rearranged B-cell acute lymphoblastic leukemia (ALL) have high rates of relapse and poor survival compared with children. Few new therapies have been identified over the past twenty years. The aim of this study was to identify existing anti-cancer agents that have the potential to be repurposed for the treatment of infant ALL.
Awards/Honours
- 2022 – Early Career Investigator Grant, Cancer Council WA, Western Australia
- 2022 – Research Establishment Fellowship, Royal Australasian College of Physicians, Australia
- 2020 – Collaborative Cancer Grant, Cancer Council WA, Australia